Neisseria meningitidis activates pyroptotic pathways in a mouse model of meningitis: role of a two-partner secretion system

Neisseria meningitidis activates pyroptotic pathways in a mouse model of meningitis: role of a two-partner secretion system

There is evidence that in infected cells in vitro the meningococcal HrpA/HrpB two-partner secretion system (TPS) mediates the exit of bacteria from the internalization vacuole and the docking of bacteria to the dynein motor resulting in the induction of pyroptosis. In this study we set out to study...

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Bibliographic Details
Main Authors: Chiara Pagliuca, Roberta Colicchio, Silvia Caterina Resta, Adelfia Talà, Elena Scaglione, Giuseppe Mantova, Leonardo Continisio, Caterina Pagliarulo, Cecilia Bucci, Pietro Alifano, Paola Salvatore
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
host-pathogen interaction
pyroptosis
Apoptosis
two-partner secretion systems
Neisseria meningitidis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1384072/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1384072/full

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