Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism

The rare sugar L-sorbose is shown to decrease cell viability and increase apoptotic cells in culture and to enhance the effect of tumor chemotherapy in combination with sorafenib in mouse xenograft models.

Bibliografiset tiedot
Päätekijät: Hui-Lin Xu, Xiaoman Zhou, Shuai Chen, Si Xu, Zijie Li, Hideki Nakanishi, Xiao-Dong Gao
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Nature Portfolio 2023-03-01
Sarja:Communications Biology
Linkit:https://doi.org/10.1038/s42003-023-04638-z