Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism
The rare sugar L-sorbose is shown to decrease cell viability and increase apoptotic cells in culture and to enhance the effect of tumor chemotherapy in combination with sorafenib in mouse xenograft models.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04638-z |
| _version_ | 1797863796757233664 |
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| author | Hui-Lin Xu Xiaoman Zhou Shuai Chen Si Xu Zijie Li Hideki Nakanishi Xiao-Dong Gao |
| author_facet | Hui-Lin Xu Xiaoman Zhou Shuai Chen Si Xu Zijie Li Hideki Nakanishi Xiao-Dong Gao |
| author_sort | Hui-Lin Xu |
| collection | DOAJ |
| description | The rare sugar L-sorbose is shown to decrease cell viability and increase apoptotic cells in culture and to enhance the effect of tumor chemotherapy in combination with sorafenib in mouse xenograft models. |
| first_indexed | 2024-04-09T22:42:28Z |
| format | Article |
| id | doaj.art-3f5076de80154fa9bca718b6f3ba1e5c |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-09T22:42:28Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-3f5076de80154fa9bca718b6f3ba1e5c2023-03-22T12:05:23ZengNature PortfolioCommunications Biology2399-36422023-03-016111710.1038/s42003-023-04638-zRare sugar l-sorbose exerts antitumor activity by impairing glucose metabolismHui-Lin Xu0Xiaoman Zhou1Shuai Chen2Si Xu3Zijie Li4Hideki Nakanishi5Xiao-Dong Gao6Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan UniversityKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan UniversityKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan UniversityKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan UniversityKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan UniversityKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan UniversityKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan UniversityThe rare sugar L-sorbose is shown to decrease cell viability and increase apoptotic cells in culture and to enhance the effect of tumor chemotherapy in combination with sorafenib in mouse xenograft models.https://doi.org/10.1038/s42003-023-04638-z |
| spellingShingle | Hui-Lin Xu Xiaoman Zhou Shuai Chen Si Xu Zijie Li Hideki Nakanishi Xiao-Dong Gao Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism Communications Biology |
| title | Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism |
| title_full | Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism |
| title_fullStr | Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism |
| title_full_unstemmed | Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism |
| title_short | Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism |
| title_sort | rare sugar l sorbose exerts antitumor activity by impairing glucose metabolism |
| url | https://doi.org/10.1038/s42003-023-04638-z |
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