Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism
The rare sugar L-sorbose is shown to decrease cell viability and increase apoptotic cells in culture and to enhance the effect of tumor chemotherapy in combination with sorafenib in mouse xenograft models.
Main Authors: | Hui-Lin Xu, Xiaoman Zhou, Shuai Chen, Si Xu, Zijie Li, Hideki Nakanishi, Xiao-Dong Gao |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-04638-z |
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