Synthesis and Anti-Proliferative Activity of 5-Benzoyl and 5-Benzylhydroxy Derivatives of 3-Amino-2-Arylcarboxamido-Thieno[2-3-<i>b</i>]Pyridines

Synthesis and Anti-Proliferative Activity of 5-Benzoyl and 5-Benzylhydroxy Derivatives of 3-Amino-2-Arylcarboxamido-Thieno[2-3-<i>b</i>]Pyridines

3-Amino-2-arylcarboxamido-thieno[2-3-<i>b</i>]pyridines have been previously described as having potent anti-proliferative activity against MDA-MB-231 and HCT116 cancer cell lines. The mechanism by which these molecules prevent cancer cell growth is proposed to be through interfering wit...

Full description

Bibliographic Details
Main Authors: Bailey Morphet, Shaun W. P. Rees, Natalie A. Haverkate, Hamid Aziz, Euphemia Leung, Lisa I. Pilkington, David Barker
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
PI-PLC
thieno[2-3-<i>b</i>]pyridines
anti-proliferative
structure–activity relationship
heterocycles
Online Access:https://www.mdpi.com/1422-0067/24/14/11407

Internet

https://www.mdpi.com/1422-0067/24/14/11407

Similar Items