Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell

Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell

Necroptosis of lung epithelial cells is regulated by aminopeptidase N levels in circulating plasma exosomes in patients and mice with sepsis-induced acute lung injury.

Bibliographic Details
Main Authors: Ting Gong, Xuedi Zhang, Zhiyong Peng, Yinfeng Ye, Ruimeng Liu, Yinggui Yang, Zhugui Chen, Zhihao Zhang, Hongfei Hu, Shuang Yin, Yi Xu, Jing Tang, Youtan Liu
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03481-y

Internet

https://doi.org/10.1038/s42003-022-03481-y

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