Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell
Necroptosis of lung epithelial cells is regulated by aminopeptidase N levels in circulating plasma exosomes in patients and mice with sepsis-induced acute lung injury.
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-06-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03481-y |
| _version_ | 1818469536919191552 |
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| author | Ting Gong Xuedi Zhang Zhiyong Peng Yinfeng Ye Ruimeng Liu Yinggui Yang Zhugui Chen Zhihao Zhang Hongfei Hu Shuang Yin Yi Xu Jing Tang Youtan Liu |
| author_facet | Ting Gong Xuedi Zhang Zhiyong Peng Yinfeng Ye Ruimeng Liu Yinggui Yang Zhugui Chen Zhihao Zhang Hongfei Hu Shuang Yin Yi Xu Jing Tang Youtan Liu |
| author_sort | Ting Gong |
| collection | DOAJ |
| description | Necroptosis of lung epithelial cells is regulated by aminopeptidase N levels in circulating plasma exosomes in patients and mice with sepsis-induced acute lung injury. |
| first_indexed | 2024-04-13T21:25:46Z |
| format | Article |
| id | doaj.art-3f5281d698f94c31a8d0899a4f235923 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-13T21:25:46Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-3f5281d698f94c31a8d0899a4f2359232022-12-22T02:29:20ZengNature PortfolioCommunications Biology2399-36422022-06-015111710.1038/s42003-022-03481-yMacrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cellTing Gong0Xuedi Zhang1Zhiyong Peng2Yinfeng Ye3Ruimeng Liu4Yinggui Yang5Zhugui Chen6Zhihao Zhang7Hongfei Hu8Shuang Yin9Yi Xu10Jing Tang11Youtan Liu12Department of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityDepartment of Anaesthetics, Affiliated Hospital of Guangdong Medical UniversityDepartment of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityDepartment of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityDepartment of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityDepartment of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityDepartment of Anesthesiology, Central People’s Hospital of ZhanjiangDepartment of Anesthesiology, The First People’s Hospital of FoshanDepartment of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityDepartment of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityDepartment of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityDepartment of Anaesthetics, Affiliated Hospital of Guangdong Medical UniversityDepartment of Anesthesiology, Shenzhen Hospital, Southern Medical UniversityNecroptosis of lung epithelial cells is regulated by aminopeptidase N levels in circulating plasma exosomes in patients and mice with sepsis-induced acute lung injury.https://doi.org/10.1038/s42003-022-03481-y |
| spellingShingle | Ting Gong Xuedi Zhang Zhiyong Peng Yinfeng Ye Ruimeng Liu Yinggui Yang Zhugui Chen Zhihao Zhang Hongfei Hu Shuang Yin Yi Xu Jing Tang Youtan Liu Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell Communications Biology |
| title | Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell |
| title_full | Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell |
| title_fullStr | Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell |
| title_full_unstemmed | Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell |
| title_short | Macrophage-derived exosomal aminopeptidase N aggravates sepsis-induced acute lung injury by regulating necroptosis of lung epithelial cell |
| title_sort | macrophage derived exosomal aminopeptidase n aggravates sepsis induced acute lung injury by regulating necroptosis of lung epithelial cell |
| url | https://doi.org/10.1038/s42003-022-03481-y |
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