A Large Case-Control Study Performed in Spanish Population Suggests That <i>RECQL5</i> Is the Only RECQ Helicase Involved in Breast Cancer Susceptibility

A Large Case-Control Study Performed in Spanish Population Suggests That <i>RECQL5</i> Is the Only RECQ Helicase Involved in Breast Cancer Susceptibility

Around 50% of the familial breast cancer (BC) cases are estimated to be caused by germline variants in known low-, moderate-, and high-risk susceptibility genes, while the other half is of unknown genetic origin. In the present study, we wanted to evaluate the role of the RECQ helicases, some of whi...

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Bibliographic Details
Main Authors: Erik Michel Marchena-Perea, Milton Eduardo Salazar-Hidalgo, Alicia Gómez-Sanz, Mónica Arranz-Ledo, Alicia Barroso, Victoria Fernández, Hugo Tejera-Pérez, Guillermo Pita, Rocío Núñez-Torres, Luz Pombo, Rafael Morales-Chamorro, Juana María Cano-Cano, Maria del Carmen Soriano, Pilar Garre, Mercedes Durán, María Currás-Freixes, Miguel de la Hoya, Ana Osorio
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
breast cancer (BC)
RECQ helicase family
next-generation sequencing
BRCAX
Online Access:https://www.mdpi.com/2072-6694/14/19/4738

Internet

https://www.mdpi.com/2072-6694/14/19/4738

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