Network and Evolutionary Analysis of Human Epigenetic Regulators to Unravel Disease Associations

Network and Evolutionary Analysis of Human Epigenetic Regulators to Unravel Disease Associations

We carried out a system-level analysis of epigenetic regulators (ERs) and detailed the protein–protein interaction (PPI) network characteristics of disease-associated ERs. We found that most diseases associated with ERs can be clustered into two large groups, cancer diseases and developmental diseas...

Full description

Bibliographic Details
Main Authors: Shinji Ohsawa, Toshiaki Umemura, Tomoyoshi Terada, Yoshinori Muto
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
protein–protein interaction
cancer disease
developmental disease
co-expression module
evolutionary rate
positive selection
Online Access:https://www.mdpi.com/2073-4425/11/12/1457

Internet

https://www.mdpi.com/2073-4425/11/12/1457

Similar Items