Targeted metabolomics suggests a probable role of the FTO gene in the kynurenine pathway in prediabetes

Background Genome-wide association studies have identified the alpha-ketoglutarate dependent dioxygenase gene (FTO) as the first susceptibility gene of obesity. In the present study, we utilized targeted metabolomics in an attempt to further elucidate mechanisms underlying the action of the FTO gene...

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Bibliographic Details
Main Authors: La-or Chailurkit, Suwannee Chanprasertyothin, Nisakron Thongmung, Piyamitr Sritara, Boonsong Ongphiphadhanakul
Format: Article
Language:English
Published: PeerJ Inc. 2022-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/13612.pdf