Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves.

The basic building blocks of the electrophysiology of cardiomyocytes are ion channels integrated in the cell membranes. Close to the ion channels there are very strong electrical and chemical gradients. However, these gradients extend for only a few nano-meters and are therefore commonly ignored in...

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Bibliographic Details
Main Authors: Karoline Horgmo Jæger, Ena Ivanovic, Jan P Kucera, Aslak Tveito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010895