Enantiotropy of Simvastatin as a Result of Weakened Interactions in the Crystal Lattice: Entropy-Driven Double Transitions and the Transient Modulated Phase as Seen by Solid-State NMR Spectroscopy

Enantiotropy of Simvastatin as a Result of Weakened Interactions in the Crystal Lattice: Entropy-Driven Double Transitions and the Transient Modulated Phase as Seen by Solid-State NMR Spectroscopy

In crystalline molecular solids, in the absence of strong intermolecular interactions, entropy-driven processes play a key role in the formation of dynamically modulated transient phases. Specifically, in crystalline simvastatin, the observed fully reversible enantiotropic behavior is associated wit...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Jiri Brus, Jiri Czernek, Martina Urbanova, Ctirad Červinka
פורמט: Article
שפה:English
יצא לאור: MDPI AG 2022-01-01
סדרה:Molecules
נושאים:
polymorphism
enantiotropy
transient modulated phase
dynamics
entropy
solid-state nuclear magnetic resonance (NMR)
גישה מקוונת:https://www.mdpi.com/1420-3049/27/3/679

אינטרנט

https://www.mdpi.com/1420-3049/27/3/679

פריטים דומים