Global characterization of extrachromosomal circular DNAs in advanced high grade serous ovarian cancer
Abstract High grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer and HGSOC patients often appear with metastasis, leading to the poor prognosis. Up to date, the extrachromosomal circular DNAs (eccDNAs) have been shown to be involved in cancer genome remodeling but t...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-04-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-04807-8 |