Global characterization of extrachromosomal circular DNAs in advanced high grade serous ovarian cancer

Global characterization of extrachromosomal circular DNAs in advanced high grade serous ovarian cancer

Abstract High grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer and HGSOC patients often appear with metastasis, leading to the poor prognosis. Up to date, the extrachromosomal circular DNAs (eccDNAs) have been shown to be involved in cancer genome remodeling but t...

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Bibliographic Details
Main Authors: Yixuan Cen, Yifeng Fang, Yan Ren, Shiyuan Hong, Weiguo Lu, Junfen Xu
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04807-8

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