Fate of the capping agent of biologically produced gold nanoparticles and adsorption of enzymes onto their surface

Abstract Enzymotherapy based on DNase I or RNase A has often been suggested as an optional strategy for cancer treatment. The efficacy of such procedures is limited e.g. by a short half-time of the enzymes or a low rate of their internalization. The use of nanoparticles, such as gold nanoparticles (...

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Bibliographic Details
Main Authors: Parastoo Pourali, Volha Dzmitruk, Miroslav Pátek, Eva Neuhöferová, Milan Svoboda, Veronika Benson
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31792-5