Identification and characterization of stromal-like cells with CD207+/low CD1a+/low phenotype derived from histiocytic lesions – a perspective in vitro model for drug testing

Identification and characterization of stromal-like cells with CD207+/low CD1a+/low phenotype derived from histiocytic lesions – a perspective in vitro model for drug testing

Abstract Background Histiocytoses are rare disorders manifested by increased proliferation of pathogenic myeloid cells sharing histological features with macrophages or dendritic cells and accumulating in various organs, i.a., bone and skin. Pre-clinical in vitro models that could be used to determi...

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Bibliographic Details
Main Authors: Agnieszka Śmieszek, Klaudia Marcinkowska, Zofia Małas, Mateusz Sikora, Martyna Kępska, Beata A. Nowakowska, Marta Deperas, Marta Smyk, Carlos Rodriguez-Galindo, Anna Raciborska
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Cancer
Subjects:
Histiocytoses
Langerhans cell histiocytosis
Rare disorders
Cell lines
In vitro study
Cellular model
Online Access:https://doi.org/10.1186/s12885-023-11807-0

Internet

https://doi.org/10.1186/s12885-023-11807-0

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