Mitochondrial Role in Intrinsic Apoptosis Induced by a New Synthesized Chalcone in Hepatocellular Carcinoma Cells

Mitochondrial Role in Intrinsic Apoptosis Induced by a New Synthesized Chalcone in Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the fourth cause of cancer-related deaths worldwide. Presently, a few drugs are available for HCC treatment and prevention, including both natural and synthetic compounds. In this study, a new chalcone, (<i>E</i>)...

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Bibliographic Details
Main Authors: Anna Santarsiero, Ilaria Pappalardo, Gabriella Margherita Rosa, Isabella Pisano, Stefano Superchi, Paolo Convertini, Simona Todisco, Patrizia Scafato, Vittoria Infantino
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
chalcone
hepatocellular carcinoma (HCC)
intrinsic pathway of apoptosis
mitochondria
BAX
BCL-2
Online Access:https://www.mdpi.com/2227-9059/10/12/3120

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https://www.mdpi.com/2227-9059/10/12/3120

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