Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells

Abstract Background Mesenchymal stem cells (MSCs) secrete a diversity of factors with broad therapeutic potential, yet current culture methods limit potency outcomes. In this study, we used topographical cues on polystyrene films to investigate their impact on the secretory profile and potency of bo...

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Bibliographic Details
Main Authors: Heizel Rosado-Galindo, Maribella Domenech
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-023-03450-0