Engineered Chimeric Peptides with IGF-1 and Titanium-Binding Functions to Enhance Osteogenic Differentiation In Vitro under T2DM Condition

Due to the complexity of the biomolecules and titanium (Ti) combination, it is a challenge to modify the implant surface with biological cytokines. The study proposed a new method for immobilizing cytokines on implant surface to solve the problem of low osseointegration under type 2 diabetes mellitu...

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Bibliographic Details
Main Authors: Jun-Jun Wang, Qian Xue, Ying-Jie Wang, Min Zhang, Yong-Jin Chen, Qian Zhang
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/15/9/3134