p53 Forms Redox-Dependent Protein–Protein Interactions through Cysteine 277

p53 Forms Redox-Dependent Protein–Protein Interactions through Cysteine 277

Reversible cysteine oxidation plays an essential role in redox signaling by reversibly altering protein structure and function. Cysteine oxidation may lead to intra- and intermolecular disulfide formation, and the latter can drastically stabilize protein–protein interactions in a more oxidizing mili...

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Bibliographic Details
Main Authors: Tao Shi, Paulien E. Polderman, Marc Pagès-Gallego, Robert M. van Es, Harmjan R. Vos, Boudewijn M. T. Burgering, Tobias B. Dansen
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Antioxidants
Subjects:
p53
cysteine oxidation
disulfide
protein–protein interaction
Online Access:https://www.mdpi.com/2076-3921/10/10/1578

Internet

https://www.mdpi.com/2076-3921/10/10/1578

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