Peripheral nerve injury and TRPV1-expressing primary afferent C-fibers cause opening of the blood-brain barrier

<p>Abstract</p> <p>Background</p> <p>The blood-brain barrier (BBB) plays the crucial role of limiting exposure of the central nervous system (CNS) to damaging molecules and cells. Dysfunction of the BBB is critical in a broad range of CNS disorders including neurodegene...

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Bibliographic Details
Main Authors: Salter Michael W, Kwan Chun, Liu Xue Jun, Beggs Simon
Format: Article
Language:English
Published: SAGE Publishing 2010-11-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/6/1/74