Impact of gas humidification and nebulizer position under invasive ventilation: preclinical comparative study of regional aerosol deposition

Abstract Successful aerosol therapy in mechanically ventilated patients depends on multiple factors. Among these, position of nebulizer in ventilator circuit and humidification of inhaled gases can strongly influence the amount of drug deposited in airways. Indeed, the main objective was to preclini...

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Bibliographic Details
Main Authors: Yoann Montigaud, Quentin Georges, Lara Leclerc, Anthony Clotagatide, Aurore Louf-Durier, Jérémie Pourchez, Nathalie Prévôt, Sophie Périnel-Ragey
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38281-9