MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis

MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis

 Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a...

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Bibliographic Details
Main Authors: Maryam Hemmatzadeh, Elham Ahangar Parvin, Alireza Ghanavatinejad, Narges Rostami, Mehrzad Hajaliloo, Navid Shomali, Hamed Mohammadi, Farhad Jadidi-Niaragh
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-12-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
MicroRNA
Natural killer cell
NK cell exhaustion
Programmed cell death protein 1
Rheumatoid arthritis
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3628

Internet

https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3628

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