Oxidative stress and lipotoxicity

The α,β polyunsaturated lipid aldehydes are potent lipid electrophiles that covalently modify lipids, proteins, and nucleic acids. Recent work highlights the critical role these lipids play under both physiological and pathological conditions. Protein carbonylation resulting from nucleophilic attack...

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Bibliographic Details
Main Authors: Amy K. Hauck, David A. Bernlohr
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520345697