Repurposing Pilocarpine Hydrochloride for Treatment of <named-content content-type="genus-species">Candida albicans</named-content> Infections

Repurposing Pilocarpine Hydrochloride for Treatment of <named-content content-type="genus-species">Candida albicans</named-content> Infections

ABSTRACT Acetylcholine modulates the virulence of Candida albicans and regulates an appropriate immune response to infection in a Galleria mellonella infection model. Indeed, the evidence suggests that C. albicans possesses a functional cholinergic receptor that can regulate filamentous growth and b...

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Bibliographic Details
Main Authors: Christopher Nile, Monica Falleni, Daniela Cirasola, Abeer Alghamdi, Oliver F. Anderson, Christopher Delaney, Gordon Ramage, Emerenziana Ottaviano, Delfina Tosi, Gaetano Bulfamante, Giulia Morace, Elisa Borghi
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mSphere
Subjects:
Candida albicans
Galleria mellonella
biofilm
muscarinic
pilocarpine hydrochloride
repurposing
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00689-18

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https://journals.asm.org/doi/10.1128/mSphere.00689-18

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