The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent

The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent

ABSTRACT Interferon alpha/beta (IFN-α/β) is a critical mediator of protection against most viruses, with host survival frequently impossible in its absence. Many studies have investigated the pathways involved in the induction of IFN-α/β after virus infection and the resultant upregulation of antivi...

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Bibliographic Details
Main Authors: Whitney C. Lane, Matthew D. Dunn, Christina L. Gardner, L. K. Metthew Lam, Alan M. Watson, Amy L. Hartman, Kate D. Ryman, William B. Klimstra
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
alphavirus
arbovirus
chikungunya virus
interferons
temperature
Online Access:https://journals.asm.org/doi/10.1128/mBio.00535-18

Internet

https://journals.asm.org/doi/10.1128/mBio.00535-18

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