Coenzyme Q Biosynthesis: An Update on the Origins of the Benzenoid Ring and Discovery of New Ring Precursors

Coenzyme Q (ubiquinone or CoQ) is a conserved polyprenylated lipid essential for mitochondrial respiration. CoQ is composed of a redox-active benzoquinone ring and a long polyisoprenyl tail that serves as a membrane anchor. A classic pathway leading to CoQ biosynthesis employs 4-hydroxybenzoic acid...

Full description

Bibliographic Details
Main Authors: Lucía Fernández-del-Río, Catherine F. Clarke
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/6/385