Normalization of voltage-sensitive dye signal with functional activity measures.

In general, signal amplitude in optical imaging is normalized using the well-established DeltaF/F method, where functional activity is divided by the total fluorescent light flux. This measure is used both directly, as a measure of population activity, and indirectly, to quantify spatial and spatiot...

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Bibliographic Details
Main Authors: Kentaroh Takagaki, Michael Thomas Lippert, Benjamin Dann, Tim Wanger, Frank W Ohl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2612132?pdf=render