The protective role of microRNA-21 against coxsackievirus B3 infection through targeting the MAP2K3/P38 MAPK signaling pathway

The protective role of microRNA-21 against coxsackievirus B3 infection through targeting the MAP2K3/P38 MAPK signaling pathway

Abstract Background The P38 mitogen-activated protein kinase (MAPK) pathway plays an essential role in CVB3-induced diseases. We previously demonstrated microRNA-21 has potential inhibitory effect on the MAP2K3 which locates upstream of P38 MAPK and was upregulated in mouse hearts upon CVB3 infectio...

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Bibliographic Details
Main Authors: Feng He, Zonghui Xiao, Hailan Yao, Sen Li, Miao Feng, Wei Wang, Zhewei Liu, Zhuo Liu, Jianxin Wu
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Translational Medicine
Subjects:
CVB3
miRNA-21
P38 MAPK
Viral release
Online Access:http://link.springer.com/article/10.1186/s12967-019-2077-y

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http://link.springer.com/article/10.1186/s12967-019-2077-y

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