Impact of HMGB1/TLR Ligand Complexes on HIV-1 Replication: Possible Role for Flagellin during HIV-1 Infection

Objective. We hypothesized that HMGB1 in complex with bacterial components, such as flagellin, CpG-ODN, and LPS, promotes HIV-1 replication. Furthermore, we studied the levels of antiflagellin antibodies during HIV-1-infection. Methods. Chronically HIV-1-infected U1 cells were stimulated with necrot...

Full description

Bibliographic Details
Main Authors: Piotr Nowak, Samir Abdurahman, Annica Lindkvist, Marius Troseid, Anders Sönnerborg
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/2012/263836