Rapid and reproducible generation of glioblastoma spheroids for high-throughput drug screening

Identifying new substances that could potentially be used for tumor therapy and the precise analysis of their spectrum of action requires models that are as similar as possible to the tumor present in the patient. Traditionally, two-dimensional (2D) cell cultures are used. However, these only resemb...

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Bibliographic Details
Main Authors: Christian Bach, Annegret Glasow, Rainer Baran-Schmidt, Henry Oppermann, Christoph Bach, Jürgen Meixensberger, Erdem Güresir, Frank Gaunitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1471012/full