A Concise Synthesis towards Antimalarial Quinazolinedione TCMDC-125133 and Its Anti-Proliferative Activity against MCF-7

A Concise Synthesis towards Antimalarial Quinazolinedione TCMDC-125133 and Its Anti-Proliferative Activity against MCF-7

Quinazolinedione is one of the most notable pharmacophores in drug discovery due to its broad spectrum of biological activities including antimalarial, anticancer, anti-inflammatory, and others. TCMDC-125133, whose structure features a quinazolinedione core, exhibits promising antimalarial activity...

Full description

Bibliographic Details
Main Authors: Sitthivut Charoensutthivarakul, Duangporn Lohawittayanan, Phongthon Kanjanasirirat, Kedchin Jearawuttanakul, Sawinee Seemakhan, Suparerk Borwornpinyo, Matthew Phanchana
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molbank
Subjects:
quinazolinedione derivatives
antimalarial activity
antiproliferative activity
Online Access:https://www.mdpi.com/1422-8599/2022/2/M1358

Internet

https://www.mdpi.com/1422-8599/2022/2/M1358

Similar Items