Accurate prediction of RNA secondary structure including pseudoknots through solving minimum-cost flow with learned potentials
Abstract Pseudoknots are key structure motifs of RNA and pseudoknotted RNAs play important roles in a variety of biological processes. Here, we present KnotFold, an accurate approach to the prediction of RNA secondary structure including pseudoknots. The key elements of KnotFold include a learned po...
Main Authors: | Tiansu Gong, Fusong Ju, Dongbo Bu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-05952-w |
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