Chemogenetic Manipulation of Amygdala Kappa Opioid Receptor Neurons Modulates Amygdala Neuronal Activity and Neuropathic Pain Behaviors

Chemogenetic Manipulation of Amygdala Kappa Opioid Receptor Neurons Modulates Amygdala Neuronal Activity and Neuropathic Pain Behaviors

Neuroplasticity in the central nucleus of the amygdala (CeA) plays a key role in the modulation of pain and its aversive component. The dynorphin/kappa opioid receptor (KOR) system in the amygdala is critical for averse-affective behaviors in pain conditions, but its mechanisms are not well understo...

Full description

Bibliographic Details
Main Authors: Guangchen Ji, Peyton Presto, Takaki Kiritoshi, Yong Chen, Edita Navratilova, Frank Porreca, Volker Neugebauer
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Cells
Subjects:
KOR
DREADD
chemogenetics
amygdala
pain
neuroplasticity
Online Access:https://www.mdpi.com/2073-4409/13/8/705

Internet

https://www.mdpi.com/2073-4409/13/8/705

Similar Items