Analyzing structural alterations of mitochondrial intermembrane space superoxide scavengers cytochrome-c and SOD1 after methylglyoxal treatment.

Mitochondria are quantitatively the most important sources of reactive oxygen species (ROS) which are formed as by-products during cellular respiration. ROS generation occurs when single electrons are transferred to molecular oxygen. This leads to a number of different ROS types, among them superoxi...

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Bibliographic Details
Main Authors: Hilda Mercado-Uribe, Mariana Andrade-Medina, Juan Horacio Espinoza-Rodríguez, Mauricio Carrillo-Tripp, Christian Quintus Scheckhuber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232408