Prognostic analysis of patients with breast cancer based on tumor mutational burden and DNA damage repair genes

Prognostic analysis of patients with breast cancer based on tumor mutational burden and DNA damage repair genes

BackgroundBreast cancer has a high tumor-specific death rate and poor prognosis. In this study, we aimed to provide a basis for the prognostic risk in patients with breast cancer using significant gene sets selected by analyzing tumor mutational burden (TMB) and DNA damage repair (DDR).MethodsBreast...

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Bibliographic Details
Main Authors: Xu Teng, Tianshu Yang, Baowen Yuan, Yunkai Yang, Jiaxiang Liu, Xin Wang, Yong Wang, Tianyu Ma, Xin Yin, Hefen Yu, Shuang Wang, Wei Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
breast cancer
TMB
cox regression analysis
Cox-LASSO regression analysis
prognostic model
tumor-infiltrating immune cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1177133/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1177133/full

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