The cwp66 Gene Affects Cell Adhesion, Stress Tolerance, and Antibiotic Resistance in Clostridioides difficile

The cwp66 Gene Affects Cell Adhesion, Stress Tolerance, and Antibiotic Resistance in Clostridioides difficile

ABSTRACT Clostridioides difficile is a Gram-positive, spore-forming anaerobic bacteria that is one of the leading causes of antibiotic-associated diarrhea. The cell wall protein 66 gene (cwp66) encodes a cell wall protein, which is the second major cell surface antigen of C. difficile. Although immu...

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Bibliographic Details
Main Authors: Qingshuai Zhou, Fengqin Rao, Zhenghong Chen, Yumei Cheng, Qifang Zhang, Jie Zhang, Zhizhong Guan, Yan He, Wenfeng Yu, Guzhen Cui, Xiaolan Qi, Wei Hong
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
Clostridioides difficile
CRISPR-Cpf1
cell wall protein 66 (Cwp66)
phenotypic analysis
transcriptome analysis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02704-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.02704-21

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