Dynamic dichotomy of accumbal population activity underlies cocaine sensitization

Locomotor sensitization (LS) is an early behavioral adaptation to addictive drugs, driven by the increase of dopamine in the Nucleus Accumbens (NAc). However, the effect on accumbal population activity remains elusive. Here, we used single-cell calcium imaging in mice to record the activity of dopam...

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Bibliographic Details
Main Authors: Ruud van Zessen, Yue Li, Lucile Marion-Poll, Nicolas Hulo, Jérôme Flakowski, Christian Lüscher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/66048