Weak Cross-Lineage Neutralization by Anti SARS-CoV-2 Spike Antibodies after Natural Infection or Vaccination Is Rescued by Repeated Immunological Stimulation

Weak Cross-Lineage Neutralization by Anti SARS-CoV-2 Spike Antibodies after Natural Infection or Vaccination Is Rescued by Repeated Immunological Stimulation

After over one year of evolution, through billions of infections in humans, SARS-CoV-2 has evolved into a score of slightly divergent lineages. A few different amino acids in the spike proteins of these lineages can hamper both natural immunity against reinfection, and vaccine efficacy. In this stud...

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Bibliographic Details
Main Authors: Sara Caucci, Benedetta Corvaro, Sofia Maria Luigia Tiano, Anna Valenza, Roberta Longo, Katia Marinelli, Monica Lucia Ferreri, Patrik Spiridigliozzi, Giovanna Salvoni, Patrizia Bagnarelli, Stefano Menzo
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Vaccines
Subjects:
COVID
SARS
neutralizing antibodies
BAU
anamnestic response
vaccine
Online Access:https://www.mdpi.com/2076-393X/9/10/1124

Internet

https://www.mdpi.com/2076-393X/9/10/1124

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