Puerarin promotes apoptosis and senescence of bladder cancer cells

Puerarin promotes apoptosis and senescence of bladder cancer cells

Objective: This study aims to explore the mechanism of puerarin regulating the proliferation, apoptosis and senescence of T24 and EJ cells via miR-139-5p/CCNB1 and PI3K/AKT pathways. Methods: Initially, Cell Counting Kit (CCK)-8, flow cytometry, β-galactosidase detection kit, and RT-qPCR are used to...

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Bibliographic Details
Main Authors: Hongbo Chen, Xiaohui Hu, Yong Lan, Su Chen, Xiaolong Xiang, Yulong Tan, Guang Zeng, Zicheng Guo, Kailing Li, Junfeng Zhang
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Journal of Functional Foods
Subjects:
Bladder cancer
Puerarin
miR-139-5p
CCNB1
PI3K/AKT
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622001025

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http://www.sciencedirect.com/science/article/pii/S1756464622001025

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