Preclinical Studies with Glioblastoma Brain Organoid Co-Cultures Show Efficient 5-ALA Photodynamic Therapy

Preclinical Studies with Glioblastoma Brain Organoid Co-Cultures Show Efficient 5-ALA Photodynamic Therapy

Background: The high recurrence of glioblastoma (GB) that occurs adjacent to the resection cavity within two years of diagnosis urges an improvement of therapies oriented to GB local control. Photodynamic therapy (PDT) has been proposed to cleanse infiltrating tumor cells from parenchyma to ameliora...

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Bibliographic Details
Main Authors: Leire Pedrosa, Carmen Bedia, Diouldé Diao, Alejandra Mosteiro, Abel Ferrés, Elisabetta Stanzani, Fina Martínez-Soler, Avelina Tortosa, Estela Pineda, Iban Aldecoa, Marc Centellas, Marta Muñoz-Tudurí, Ana Sevilla, Àngels Sierra, José Juan González Sánchez
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
5-ALA
3D tumor models
neurological cancers
drug screening
glioblastoma
organoids
Online Access:https://www.mdpi.com/2073-4409/12/8/1125

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https://www.mdpi.com/2073-4409/12/8/1125

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