Computational Characterization of Membrane Proteins as Anticancer Targets: Current Challenges and Opportunities

Computational Characterization of Membrane Proteins as Anticancer Targets: Current Challenges and Opportunities

Cancer remains a leading cause of mortality worldwide and calls for novel therapeutic targets. Membrane proteins are key players in various cancer types but present unique challenges compared to soluble proteins. The advent of computational drug discovery tools offers a promising approach to address...

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Bibliographic Details
Main Authors: Marina Gorostiola González, Pepijn R. J. Rakers, Willem Jespers, Adriaan P. IJzerman, Laura H. Heitman, Gerard J. P. van Westen
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
computational drug discovery
membrane protein
cancer
anticancer target
receptor tyrosine kinase
RTK
Online Access:https://www.mdpi.com/1422-0067/25/7/3698

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https://www.mdpi.com/1422-0067/25/7/3698

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