Persistence of intact HIV-1 proviruses in the brain during antiretroviral therapy

HIV-1 reservoir cells that circulate in peripheral blood during suppressive antiretroviral therapy (ART) have been well characterized, but little is known about the dissemination of HIV-1-infected cells across multiple anatomical tissues, especially the CNS. Here, we performed single-genome, near fu...

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Bibliographic Details
Main Authors: Weiwei Sun, Yelizaveta Rassadkina, Ce Gao, Sarah Isabel Collens, Xiaodong Lian, Isaac H Solomon, Shibani S Mukerji, Xu G Yu, Mathias Lichterfeld
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/89837