Regulation of interferon gamma signaling by suppressors of cytokine signaling and regulatory T cells
Regulatory T cells (Tregs) play an indispensable role in the prevention of autoimmune disease, as interferon gamma (IFN) mediated, lethal autoimmunity occurs (in both mice and humans) in their absence. In addition, regulatory T cells have been implicated in preventing the onset of autoimmune and a...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-12-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00469/full |