Efficacy and safety of two incobotulinumtoxinA injection intervals in cervical dystonia patients with inadequate benefit from standard injection intervals of botulinum toxin: Phase 4, open-label, randomized, noninferiority study

IntroductionSome patients with cervical dystonia (CD) receiving long-term botulinum neurotoxin (BoNT) therapy report early waning of treatment benefit before the typical 12-week reinjection interval. Methods: This phase 4, open-label, randomized, noninferiority study (CD Flex; NCT01486264) compared...

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Main Authors: Cynthia Comella, Robert A. Hauser, Stuart H. Isaacson, Daniel Truong, Odinachi Oguh, Jennifer Hui, Eric S. Molho, Matthew Brodsky, Erin Furr-Stimming, Georg Comes, Michael A. Hast, David Charles
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Clinical Parkinsonism & Related Disorders
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590112522000135