Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis.

Phenolic glycolipids are produced by a very limited number of slow-growing mycobacterial species, most of which are pathogen for humans. In Mycobacterium tuberculosis, the etiologic agent of tuberculosis, these molecules play a role in the pathogenicity by modulating the host immune response during...

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Bibliographic Details
Main Authors: Roxane Simeone, Gaëlle Huet, Patricia Constant, Wladimir Malaga, Anne Lemassu, Françoise Laval, Mamadou Daffé, Christophe Guilhot, Christian Chalut
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3594219?pdf=render