Intranasal creatine administration increases brain creatine level and improves Barnes maze performance in rats

While skeletal muscle creatine levels can be enhanced by exogenous creatine supplementation, the elevation of brain creatine levels with oral creatine administration remains a challenge due to a lack of effective transportation of creatine through the blood-brain barrier. Intranasal administration c...

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Bibliographic Details
Main Authors: Kaiqing Chen, Xiaoping Hu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Brain Research Bulletin
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023001284