Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys

Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys

HIV infection results in the depletion of CD4+ T cells overtime and the loss of coordinated cellular immunity, but how this corresponds to the SIV infected African Green Monkey (AGM) model of non-progressive disease is not known. Here the authors assess the impact of experimental CD4+ T cell depleti...

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Bibliographic Details
Main Authors: Quentin Le Hingrat, Paola Sette, Cuiling Xu, Andrew R. Rahmberg, Lilas Tarnus, Haritha Annapureddy, Adam Kleinman, Egidio Brocca-Cofano, Ranjit Sivanandham, Sindhuja Sivanandham, Tianyu He, Daniel J. Capreri, Dongzhu Ma, Jacob D. Estes, Jason M. Brenchley, Cristian Apetrei, Ivona Pandrea
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36379-2

Internet

https://doi.org/10.1038/s41467-023-36379-2

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