Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys
HIV infection results in the depletion of CD4+ T cells overtime and the loss of coordinated cellular immunity, but how this corresponds to the SIV infected African Green Monkey (AGM) model of non-progressive disease is not known. Here the authors assess the impact of experimental CD4+ T cell depleti...
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Bibliographic Details
| Main Authors: |
Quentin Le Hingrat,
Paola Sette,
Cuiling Xu,
Andrew R. Rahmberg,
Lilas Tarnus,
Haritha Annapureddy,
Adam Kleinman,
Egidio Brocca-Cofano,
Ranjit Sivanandham,
Sindhuja Sivanandham,
Tianyu He,
Daniel J. Capreri,
Dongzhu Ma,
Jacob D. Estes,
Jason M. Brenchley,
Cristian Apetrei,
Ivona Pandrea |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2023-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-023-36379-2
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