Development of stealth liposomal formulation of celecoxib: In vitro and in vivo evaluation.

Development of stealth liposomal formulation of celecoxib: In vitro and in vivo evaluation.

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Celecoxib (CLB) is a highly hydrophobic selective cyclo-oxygenase inhibitor with high plasma protein binding and undergoes extensive hepatic metabolism. CLB is highly effective in the treatment of osteo and rheumatoid arthritis as first line therapy but produces severe gastro-intestinal toxicities a...

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Bibliographic Details
Main Authors: M Yasmin Begum, Riyaz Ali M Osmani, Ali Alqahtani, Mohammed Ghazwani, Umme Hani, Hissana Ather, Akhtar Atiya, Mohamed Rahamathulla, Ayesha Siddiqua
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0264518

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https://doi.org/10.1371/journal.pone.0264518

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